Vitamin B12 Methylcobalamin Powder: Premium Raw Material for Dietary Supplements

As a leading Vitamin B12 Methylcobalamin supplier, Oclean Nutra provides high-purity, pharmaceutical-grade Methylcobalamin Powder to support global health brands in creating effective nutritional supplements. This comprehensive guide details the science, benefits, and specifications of this essential nutrient.

What is Vitamin B12 Methylcobalamin Powder?

Vitamin B12 Methylcobalamin Powder is the predominant, biologically active coenzyme form of Vitamin B12 (Cobalamin). Unlike cyanocobalamin, a synthetic form that requires metabolic conversion, methylcobalamin is naturally occurring and readily bioavailable. This high-purity Methylcobalamin powder appears as a dark red, crystalline, and hygroscopic powder. It is the form directly involved in the methionine synthase cycle, making it a superior choice for advanced nutraceutical formulations targeting neurological health and efficient homocysteine metabolism. For bulk supplement production, its consistent physical characteristics ensure excellent blend uniformity.

Sources and Biosynthesis

Methylcobalamin is not synthesized by plants or animals but exclusively by certain microorganisms. Therefore, commercial-grade Bulk Methylcobalamin is produced via controlled microbial fermentation. This process utilizes specific bacterial strains (e.g., Pseudomonas denitrificans, Propionibacterium freudenreichii) in large-scale bioreactors. This method guarantees a sustainable, scalable, and contaminant-free source of this essential nutrient, aligning with the stringent requirements of a reliable B2B ingredient supplier.

The Efficacy and Applications in Formulation

The efficacy of Methylcobalamin Powder is rooted in its role as a cofactor for two crucial enzymes:

Methionine Synthase: Facilitates the conversion of homocysteine to methionine, which is vital for nucleotide methylation, neurotransmitter production, and myelin sheath maintenance.
L-Methylmalonyl-CoA Mutase: Catalyzes a step in energy production from fats and proteins.

These actions make Methylcobalamin for supplement manufacturing particularly effective for:

Cognitive and Neurological Support Formulations
Cardiovascular Health Products (via homocysteine reduction)
Energy Metabolism and Sports Nutrition Supplements
Targeted formulations for vegetarians, seniors, and individuals with specific absorption concerns

Its high bioavailability ensures that end-products deliver efficacious results, a key consideration for wholesale Vitamin B12 buyers.

Production Process and Quality Assurance

The production of our high-purity Vitamin B12 Methylcobalamin Powder is a multi-stage, rigorously controlled process:

1.Fermentation: Selected bacterial strains are cultured in a optimized nutrient medium under sterile conditions.
2.Extraction and Purification: The biomass is harvested, and the cobalamins are released through cell lysis. Subsequent purification steps, including chromatography, isolate Methylcobalamin from other cobalamin forms.
3.Crystallization: The purified extract is crystallized to obtain the final powder form with defined particle size distribution.
4.Quality Control (Lab Testing): Every batch of our Bulk Vitamin B12 undergoes exhaustive lab testing via High-Performance Liquid Chromatography (HPLC) for potency and identity, alongside tests for heavy metals, microbial limits, and residual solvents. This commitment to GMP standards ensures a consistently safe and potent raw material.

Packaging, Services & Inquiry

Minimum Order Quantity (MOQ): 1 kg
Free Sample: Available (10-20g/bag) for qualified businesses.
Custom Services: Full support for OEM, ODM, Private Label, and Contract Manufacturing.
Standard Packaging: 1 kg/bag, 25 kg/drum. Custom packaging available.
Shelf Life: 24 months in a cool, dry place away from light.

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Side Effects and Safety Profile

Vitamin B12 Methylcobalamin is generally recognized as safe (GRAS) with an excellent safety profile. As a water-soluble vitamin, any excess is efficiently excreted via urine. There are no known toxicity levels associated with high intakes. As a responsible manufacturer, we recommend that our clients adhere to established regulatory guidelines for dosage in their final product labeling.

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