Thiamine HCl (Thiamine Hydrochloride)
| Product Name | Thiamine Hydrochloride (Vitamin B1 HCl) |
| Aliases | Thiamine HCl, Aneurine Hydrochloride, Vitamin B1 Monochloride |
| CAS Number | 67-03-8 |
| Molecular Formula | C12H18Cl2N4OS |
| Molecular Weight | 337.27 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥98% (HPLC) |
| Packages | 1kg,5kg/bag, 25kg/drum |
Thiamine HCl (Vitamin B1 Hydrochloride) - Premium Bulk Powder
A high-purity, essential nutrient designed for global manufacturers seeking reliable and effective ingredients for their nutritional products, food fortification programs, and animal feed solutions.
What is Thiamine HCl? An Essential Nutrient in Its Purest Form
Thiamine Hydrochloride, chemically known as Thiamine HCl, is the stable hydrochloride salt form of Vitamin B1. As a fundamental, water-soluble vitamin, it is an indispensable nutrient required by all living organisms for basic metabolic functions. In its pure form, it presents as a white or almost white, free-flowing crystalline powder, highly valued in manufacturing for its exceptional purity, consistent quality, and excellent solubility profile.
This compound serves as a direct precursor to Thiamine Pyrophosphate (TPP), the active coenzyme crucial for energy production. Its critical role in cellular metabolism makes it a cornerstone ingredient for a wide spectrum of nutritional and health product formulations worldwide, ensuring end-products deliver on their promised health benefits.
Natural Occurrence vs. Concentrated Supply: Sourcing Thiamine HCl
While Thiamine is naturally present in various food sources such as whole grains, legumes, pork, and nuts, the levels can be variable and often insufficient for therapeutic or fortification purposes. The concentrated Thiamine Hydrochloride used in commercial manufacturing is produced through advanced and controlled synthetic processes. This method guarantees a consistent, high-potency, and cost-effective supply for bulk ingredient buyers who require a reliable and standardized raw material for their large-scale production needs.
Unlocking Metabolic Potential: The Efficacy and Mechanism of Thiamine HCl
The profound efficacy of Thiamine HCl is rooted in its biochemical role as a precursor to Thiamine Pyrophosphate (TPP), a vital coenzyme in key metabolic pathways. Its primary mechanisms of action are essential for health and vitality:
- Central Role in Energy Metabolism: TPP is a critical cofactor for enzymes involved in the citric acid cycle and the pentose phosphate pathway. It is fundamentally responsible for facilitating the conversion of dietary carbohydrates into adenosine triphosphate (ATP), the primary energy currency of the cell. This makes it indispensable for products aimed at supporting energy, reducing fatigue, and enhancing metabolic vitality.
- Crucial Support for Nervous System Health: The proper functioning of the nervous system is heavily dependent on Thiamine. TPP is required for the synthesis of acetylcholine, a key neurotransmitter, and for the maintenance of myelin sheaths around nerves. Adequate levels are crucial for cognitive function and neurological integrity.
- A Pillar of Public Health and Food Fortification: Due to its essential role in preventing deficiency diseases like beriberi, Thiamine HCl is a mandated ingredient in public health initiatives. Its inclusion in staple foods such as flour, rice, and cereals is a global strategy to ensure population-wide nutritional adequacy.
For manufacturers, this well-established efficacy provides a powerful, science-backed foundation for your energy-boosting supplements, fortified food products, and therapeutic nutritional formulas.
A Glimpse into the Manufacturing: How is Thiamine HCl Produced?
The industrial-scale production of Thiamine HCl is a sophisticated multi-step chemical synthesis process, optimized for maximum yield, purity, and consistency. It involves precise condensation reactions, cyclization steps, and multiple stages of rigorous purification and crystallization to achieve the final high-grade crystalline powder. As a dedicated Thiamine HCl manufacturer, we implement stringent quality control checkpoints throughout this entire process. This ensures that every batch delivered meets the exacting specifications required for identity, potency, and purity, making it a reliable choice for demanding manufacturing applications.
Product Specifications: Thiamine HCl (Vitamin B1 Hydrochloride) Powder
For B2B partners requiring detailed technical documentation. A comprehensive, batch-specific Certificate of Analysis (COA) will be provided promptly upon request.
| Parameter | Specification | Test Method |
|---|---|---|
| Identity | ||
| Product Name | Thiamine Hydrochloride | - |
| CAS No. | 67-03-8 | - |
| Appearance | White or almost white crystalline powder | Visual Inspection |
| Key Specifications | ||
| Assay (Purity) | 98.5% - 101.5% | HPLC |
| Loss on Drying | ≤ 5.0% | Karl Fischer Titration |
| Residue on Ignition | ≤ 0.1% | Gravimetric Analysis |
| Identification | Complies with USP Reference Standard | IR Spectroscopy |
| Safety & Quality | ||
| Heavy Metals | ||
| - Lead (Pb) | ≤ 3.0 mg/kg | ICP-MS |
| - Arsenic (As) | ≤ 1.0 mg/kg | ICP-MS |
| - Cadmium (Cd) | ≤ 1.0 mg/kg | ICP-MS |
| - Mercury (Hg) | ≤ 0.1 mg/kg | ICP-MS |
| Total Plate Count | ≤ 1000 CFU/g | USP <61> |
| Yeast & Mold | ≤ 100 CFU/g | USP <61> |
| E. Coli | Negative | USP <62> |
| Salmonella | Negative | USP <62> |
| Certifications | ISO 9001, GMP (Certificates available upon request) | Audit Certification |
Note: The specifications above define our standard Thiamine HCl product profile. We also provide customization options—such as adjustments to particle size and packaging—to meet specific formulation requirements. Contact us to request the full Certificate of Analysis (COA) for detailed, batch-specific data and supporting compliance documentation.
Packaging, Services & Inquiry
- Minimum Order Quantity (MOQ): 1 kg
- Free Sample: Available (10-20g/bag) for qualified businesses.
- Custom Services: Full support for OEM, ODM, Private Label, and Contract Manufacturing.
- Standard Packaging: 1 kg/bag, 25 kg/drum. Custom packaging available.
- Shelf Life: 24 months in a cool, dry place away from light.
Request a Free Sample & Full Datasheet | Get a Quote for Bulk Order
Safety Profile and Potential Side Effects of Thiamine HCl
Thiamine HCl is generally recognized as safe (GRAS) for its intended uses in food, supplements, and animal feed. As a water-soluble vitamin, it has a high safety margin, with any excess beyond the body's physiological needs typically being efficiently excreted through urine. Adverse effects associated with high doses are exceedingly rare. As with any raw material, it is imperative for manufacturers to adhere to established recommended usage levels and regulatory guidelines within their final product formulations to ensure safety and efficacy.